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Symbol
Name
ID 		Sod2
superoxide dismutase 2, mitochondrial
MGI:98352
Phenotype annotations related to immune system
Darker colors indicate more annotations
Human Phenotypes
Increased circulating IgA level
Increased circulating IgG level
Decreased circulating antibody level
Paraproteinemia
Leukopenia
Acute myeloid leukemia
Pericarditis
Lymphadenopathy
Splenomegaly
Hepatosplenomegaly
Peritoneal abscess
Subacute progressive viral hepatitis
Lupus nephritis
Nephritis
Abnormality of the immune system
Acne
Skin rash
Discoid lupus rash
Malar rash
Serositis
Decreased circulating complement C3 concentration
Decreased circulating complement C4 concentration
Autoimmunity
Antineutrophil antibody positivity
Perinuclear antineutrophil antibody positivity
Antinuclear antibody positivity
Anti-dsDNA antibody positivity
Anti-La/SS-B antibody positivity
Anti-Sm antibody positivity
Anti-U1 ribonucleoprotein antibody positivity
Antiphospholipid antibody positivity
Systemic lupus erythematosus
Asthma
Disease(s) Associated with SOD2
acute myeloid leukemia
asthma
hepatocellular carcinoma
inclusion body myositis
multiple myeloma
pancreatic cancer
pseudoxanthoma elasticum
systemic lupus erythematosus
type 1 diabetes mellitus

Mouse Phenotypes
impaired myelopoiesis
Availability Mouse Genotype
Sod2tm1Leb/Sod2tm1Leb
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory